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4 Beds
2 Baths
2,000 sqft

$449,000

621 Main Street, Lewiston ME, 04240

Built in1906
Property size2,000 sqft
Property typeResidential
Courtesy of Signature Homes Real Estate Group

Overview

Active

Listed May 20, 2026

Updated 43h ago

Unlock the potential of this flexible downtown Main Street space in the heart of Lewiston's growing commercial corridor. Located at 621 Main Street, this versatile commercial property presents an exceptional opportunity for entrepreneurs, investors, and owner-occupants alike. Positioned along a high-visibility corridor with strong daily traffic counts, the property offers outstanding exposure for a wide variety of business uses while also providing the unique opportunity to create a private residential living space on the second floor. The first floor features adaptable commercial space ideal for retail, professional office, creative studio, service-based businesses, or a mixed-use concept. Its prominent street presence helps attract customers and clients, while ample off-street parking provides added convenience and accessibility. The second floor offers the potential to be transformed into a comfortable residence, creating the perfect live-work environment or an additional source of rental income. Conveniently located near downtown amenities, restaurants, and major commuter routes, 621 Main Street combines excellent visibility, flexibility, and long-term investment potential. Whether you're launching a new business, expanding your portfolio, or envisioning a dynamic live-work property, this well-positioned building offers endless possibilities in one of Lewiston's evolving commercial districts. Also listed as MLS# 1662884

$2,987/mo

Est. mortgage payment based on a $449,000 home price.

All estimates are provided by Luxury Presence for informational purposes only. Actual amounts may vary.

Additional information

MLS® ID
1662959

Interior Features

Bedrooms
4
Bathrooms
2
Fireplace
Yes
Cooling
Yes
Heating
Yes
Basement
Yes

Exterior Features

Lot Size
0.17 Acres

Other Property Details

Taxes
$3,780
Tax Frequency
Annually
Furnished
Yes
MLS provider logo

Listing Contact: 207-838-8051

Listed by Tiffany Libby Pamela Starnes with Signature Homes Real Estate Group 207-838-8051

Listing data is derived in whole or in part from the Maine IDX and is for consumers' personal, noncommercial use only. Dimensions are approximate and not guaranteed. All data should be independently verified. © 2026 Maine Real Estate Information System, Inc. All Rights Reserved. All information deemed reliable but not guaranteed and should be independently verified. All properties are subject to prior sale, change, or withdrawal. Neither listing broker(s) nor Patti Foden shall be responsible for any typographical errors, misinformation, misprints and shall be held totally harmless.

©2026 Maine Real Estate Information System, Inc. All rights reserved. 

Data is refreshed every 3 hours. Listing last updated at 3:54 AM UTC, 10/10/2026

 

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